副研究員
黃曉蓓，中國科學(xué)院重慶綠色智能技術(shù)研究院，副研究員，重慶市科技特派專家，，工學(xué)博士。2017年博士畢業(yè)于四川大學(xué)生物醫(yī)學(xué)工程專業(yè)。愛爾蘭都柏林大學(xué)公派聯(lián)合培養(yǎng)博士，澳門大學(xué)博士后。2024入選重慶市青年創(chuàng)新人才。
主要研究方向?yàn)殚_發(fā)可用于生物醫(yī)藥領(lǐng)域的新型仿生高分子材料。目前以第一作者（共一）或通訊作者（共通）在一區(qū)雜志Journal of Controlled Release、Acta Biomaterialia、ACS Macro Letters、Chemical Communications等頂級期刊發(fā)表學(xué)術(shù)論文20余篇，其中IF>10的6篇，高被引1篇。主持國家自然科學(xué)基金、重慶市自然科學(xué)基金等科研項(xiàng)目10余項(xiàng)。申請國家發(fā)明專利3項(xiàng)，獲批2項(xiàng)。《Supramolecular Materials》青年編委。
干細(xì)胞與衰老研究中心
生物醫(yī)用高分子，藥物遞送，基因遞送
2022年 院優(yōu)秀特別助理研究員
2023年 院優(yōu)秀員工
2024年 院優(yōu)秀員工
1. Xiaobei Huang a,*, Ning Mu b,1, Yuanfu Ding d,1, Rong Huang a, Wei Wu e,*, Li Li a,*, Tunan Chen b,c,*. Tumor microenvironment targeting for glioblastoma multiforme treatment via hybrid cell membrane coating supramolecular micelles. Journal of Controlled Release. 2024 , 336, 194-203.?
2. Yongguo Xiang#, Zhu Qiu#, Yuanfu Ding, Miaomiao Du, Ning Gao, Huijie Cao, Hangjia Zuo, Hong Cheng, Xiang Gao, Shijie Zheng, Wenjuan Wan, Xiaobei Huang*, Ke Hu*. Dexamethasone-loaded ROS Stimuli-responsive Nanogels for Topical Ocular Therapy of Corneal Neovascularization. Journal of Controlled Release. 2024, 372, 874-884.
3. Li Zhu, Yuan Zhong, Meng Yan, Sheng Ni, Xiong Zhao, Shuai Wu, Guixue Wang,Kai Qu, Kun Zhang, Qingjia Chi, Xian Qin,* Chuanwei Li,* Xiaobei Huang,* Wei Wu,*, Macrophage Membrane-Encapsulated Dopamine-Modified Poly Cyclodextrin Multifunctional Biomimetic Nanoparticles for Atherosclerosis Therapy. ACS Applied Materials & Interfaces. 2024, 16, 25, 32027-32044.
4. Shengyun Hu?, Kunkun Xia?, Xiaobei Huang?, Ye Zhao, Qingqing Zhang, Dongdong Huang, Weiyi Xu, Zhengju Chen*, Chenfei Wang* and Zhiyong Zhang*, Multifunctional CaCO3@Cur@QTX125@HA nanoparticles for efectively inhibiting growth of colorectal cancer cells. Journal of Nanobiotechnology. 2023, 21:353.
5. Jiahao Shi, Bin Ma, Yuhe Zhang, Haiyang Yong, Zhili Li, Sigen A*, Xiaobei Huang*, and Dezhong Zhou*. Targeted Delivery of Anticancer Therapeutics with Polymers by Harnessing Tumor Microenvironment Acidity. Chemistry of Materials. 2023, 35 (17), 6573-6590.
6. Xiaobei Huang, Ning Mu, Yuanfu Ding, Hou Wang Lam, Ludan Yue, Cheng Gao, Tunan Chen,* ZhenYuan* and Ruibing Wang*, Targeted delivery and enhanced uptake of chemo-photodynamic nanomedicine for melanoma treatment. Acta Biomaterialia. 2022, 147, 356-365.
7. Xiaobei Huang,? Tunan Chen,? Ning Mu, Hou Wang Lam, Chen Sun, Ludan Yue, Qian Cheng, Cheng Gao, Zhen Yuan* and Ruibing Wang*, Supramolecular micelles as multifunctional theranostic agents for synergistic photodynamic therapy and hypoxia-activated chemotherapy. Acta? Biomaterialia. 2021, 131, 483-492.?
8. Chenfei Wang,? Xiaobei Huang,? Litao Sun, Qiuxia Li, ZhiliLi, Haiyang Yong, Delu Che, Cong Yan, Songmei Geng,*Wenxin Wang and Dezhong Zhou*, Cyclic poly(?-amino ester)s with enhanced gene transfection activity synthesized through intra-molecular cyclization. Chemical Communications. 2022, DOI: 10.1039/d1cc06480k.?
9. Qiuxia Li,? Litao Sun,? Xiaobei Huang,? Shuai Liu,* Haiyang Yong, Chenfei Wang, Jianzhong Li,* and Dezhong Zhou*, Genetic Engineering of Adipose-Derived Stem Cells Using Biodegradable and Lipid-Like Highly Branched Poly(β-amino ester)s. ACS Macro Letters. 2022, 11, 636-642.
10. Haiyang Yong,# Zhili Li,# Xiaobei Huang,# Kaixuan Wang, Ya-Nan Zhou, Qiuxia Li, Jianjun Shi,* Ming Liu, Dezhong Zhou.*, Superhydrophobic Materials: Versatility and Translational Applications. Advanced materials interfaces. 2022, 2200435.?
1、國自然青年科學(xué)基金項(xiàng)目，《仿生“雙鎖”超分子組裝體抗腦膠質(zhì)瘤的效應(yīng)研究》，2025-2027，
5240031367，30萬，主持。?
2、新重慶青年創(chuàng)新人才項(xiàng)目，《仿生超分子組裝體抗腦膠質(zhì)瘤的效應(yīng)研究》，2025-2027，2024NSCQ-qncxX0306，60萬，主持。
3、國家生豬創(chuàng)新中心先導(dǎo)科技項(xiàng)目，《永生化細(xì)胞系構(gòu)建》，2022-2024，NCTIP-XD/B1332000576，60萬，主持。
4、重慶市自然科學(xué)基金面上項(xiàng)目，《基于多形性膠質(zhì)母細(xì)胞瘤的雜化細(xì)胞膜包覆納米藥物的同源靶向遞送機(jī)制及個(gè)性化治療研究》，2023-2025，CSTB2023NSCQ-MSX1077，5萬，主持。
5、中國科學(xué)院重慶綠色智能技術(shù)研究院基礎(chǔ)研究課題，《仿生超分子組裝體抗腫瘤的效應(yīng)研究》，2024-2026，25萬，主持。
6、重慶榮昌農(nóng)牧高新技術(shù)產(chǎn)業(yè)研發(fā)專項(xiàng)，《表達(dá)人抗體基因工程豬的培育》，2020-2023，cstc2020ngzx0001，40萬，主持。
7、重慶市留創(chuàng)計(jì)劃，5萬，主持。
中國科學(xué)院重慶綠色智能技術(shù)研究院 版權(quán)所有京ICP備05002857號(hào)渝公網(wǎng)安備50010943035號(hào)
